Family Guy

Season 15, Episode 6

Episode Title: Hot Shots

Air Date: 2016-11-13

Overview:

In order to "save" Stewie from autism, Peter and Lois decide not to vaccinate him and then proceed to convince the rest of Quahog to follow suit. Stewie runs away to save himself from diseases until Sean Penn swoops in to save the day and brings vaccines to the whole town.